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Supplementation or approaches that increase endogenous synthesis, such as N-acetylcysteine, glycine, and cysteine availability, demonstrate measurable improvements in oxidative stress markers and, in some studies, improved fertilization outcomes

If fever, chills, or other unexpected systemic reactions occur during an injection, it is likely due to the drug being delivered or possible contamination, rather than the bacteriostatic water itself

Individuals with pernicious anemia, characterized by a lack of intrinsic factor, are also particularly susceptible